Dapsone, danazol, and intrapartum splenectomy in refractory ITP complicating pregnancy.
نویسندگان
چکیده
Currently there is no consensus on the treatment of refractory idiopathic thrombocytopenic purpura (ITP) complicating pregnancy. Our patient with chronic ITP complicating pregnancy, who was refractory to steroids, dapsone, and danazol, was treated successfully with intrapartum splenectomy.
منابع مشابه
Immunomodulatory treatments for persistent and chronic immune thrombocytopenic purpura
BACKGROUND Corticosteroid sparing is required in 15% to 40% of adults with persistent or chronic primary immune thrombocytopenic purpura (ITP). Herein, the efficacy of immunomodulatory drugs (dapsone, interferon alpha, danazol, and hydroxychloroquine as second-third-line therapies in ITP is investigated. METHODS MEDLINE was searched for studies that included patients with persistent or chroni...
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BACKGROUND Dapsone has been recommended as a second-line immunosuppressive agent for patients with immune thrombocytopenia (ITP). METHODS We retrospectively analyzed the efficacy and safety of dapsone therapy in patients with ITP. RESULTS Nine ITP patients were treated with dapsone at a dose of 50-100 mg/day between May 2013 and March 2016. All patients were refractory to multiple previous ...
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ورودعنوان ژورنال:
- Indian journal of medical sciences
دوره 62 11 شماره
صفحات -
تاریخ انتشار 2008